Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 12557676 | HCID 12557676 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 12557679 | HCID 12557679 | — |
Reaction Steps
A solution at -25° C. of 2-methoxy-7-[N-[(4-methylphenyl)-sulfonyl]-N-methylamino]-2,4,6-cycloheptatrien-1-one (described above, 4.0 g) in methanol (40 ml) is saturated with ammonia gas and heated in a pressure bottle at 80° C. for 4 hours. The solution is cooled to -70° C., the bottle is opened and the solvent is evaporated to yield 2-amino-7-[N-[(4-methylphenyl)sulfonyl]-N-methylamino]-2,4,6-cycloheptatrien-1-one, mp 221°-222° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04183955 |
|---|
| Source dataset | uspto-grants-1980_01 |
|---|
| ORD ID | ord-8d468e91cac1466a8d1a240b317e5fa1 |
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| Source note | uspto-grants-1980_01 |
|---|
