HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → HCID 20376624, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Methylcyclopropane-1-carbonyl chloride | HCID 12789939 | — |
| Reactant | HCID 20376640 | HCID 20376640 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 20376624 | HCID 20376624 | 86% |
Reaction Steps
To a solution of 6.7 g (0.025 mole) of the aniline prepared as in (c) above and 2.5 g of triethylamine in 50 ml of tetrahydrofuran was added dropwise 3.0 g (0.025 mole) of 1-methylcyclopropanecarboxylic chloride. The mixture was refluxed for one hour, poured into ice water, filtered and recrystallized from methanol to give 7.5 g (86%) of product as a white crystalline solid; m.p. 153°-156° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04184867 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-af7821ecbb7f4e788f19c92804d6cc3c |
| Source note | uspto-grants-1980_01 |