Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 205245Generated: October 25, 2026

Dichloromethane → 7-Chloro-2-(4-trifluoromethoxy-benzyl)-5-trimethylsilanylethynyl-2,3-dihydro-isoindol-1-one

https://huagongshe.com/reaction/205245

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylamineHCID 7912—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethyl-2-propynylsilaneHCID 83378—
Reactant5-Bromo-7-chloro-2-(4-trifluoromethoxybenzyl)-2,3-dihydroisoindol-1-oneHCID 11704475—
Product7-Chloro-2-(4-trifluoromethoxy-benzyl)-5-trimethylsilanylethynyl-2,3-dihydro-isoindol-1-oneHCID 57949545—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-fbd90757f57045e9924e03c60166d8f8
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)