HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 27126-29-0
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Benzoic acid, 4-[[(4-methoxyphenyl)methyl]amino]-, ethyl ester | HCID 4435805 | — |
| Reactant | Water ethanol | HCID 19096565 | — |
| Solvent | Water | HCID 962 | — |
| Product | 27126-29-0 | HCID 2731039 | — |
Reaction Steps
A mixture of 15 g. of ethyl p-[(p-methoxybenzyl)amino]benzoate, (prepared as described in Example 14) 15 g. of potassium hydroxide and 200 ml. of ethanol-water (9:1) are refluxed for 3 hours, acidified while hot with concentrated hydrochloric acid, diluted with water, cooled, filtered and the solid is washed with water to give tan crystals, m.p. 208°-210° C. Recrystallization from ethanol gives off-white crystals, m.p. 209°-210° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04185115 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-b5a206199f9b42608185f530b0ee1fe5 |
| Source note | uspto-grants-1980_01 |