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Acetone → 3,4-Dimethyl-2(3H)thiazolone-(1-methylethylidene)hydrazone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetone | HCID 180 | — |
| 反応物 | Chloroacetone | HCID 6571 | — |
| 反応物 | N-Methylhydrazinecarbothioamide | HCID 2723853 | — |
| 生成物 | 3,4-Dimethyl-2(3H)thiazolone-(1-methylethylidene)hydrazone | HCID 73414809 | — |
反応手順
21 g (200 mmol) of 4-methyl-3-thiosemicarbazide in 1000 mL of acetone was heated at reflux for 2 hours. To the solution was then added dropwise 20.4 g (220 mmol) of chloroacetone. The reaction mixture was heated at reflux for 7 hours and concentrated. The resulting crude product was recrystallized from acetone. This gave 23 g of an orange powder (63% of the theoretical).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07326254B2 |
| 出典データセット | uspto-grants-2008_02 |
| ORD ID | ord-3354a96ad0934a8b8256b541dc25fbd1 |
| 出典メモ | uspto-grants-2008_02 |