HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 1-(Benzyloxy)-4-bromo-2-fluorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | 4-Bromo-2-fluorophenol | HCID 2724981 | — |
| Product | 1-(Benzyloxy)-4-bromo-2-fluorobenzene | HCID 18757491 | 99.4% |
Reaction Steps
Analogously to the synthesis described above (under Example 2.1 or 872.1), 250 g (1.31 mol) of 4-bromo-2-fluorophenol and 179 ml (1.51 mol) of benzyl bromide gave 366 g (97%) of 1-benzyloxy-4-bromo-2-fluorobenzene as colourless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326447B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-4da90700abd140fcb5fbdf816004e304 |
| Source note | uspto-grants-2008_02 |