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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2052780Generated: October 31, 2026

4-Hydroxybenzaldehyde → p-Dodecyloxybenzaldehyde

https://huagongshe.com/reaction/2052780

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-HydroxybenzaldehydeHCID 126—
Reactant1-BromododecaneHCID 8919—
ReactantPotassium CarbonateHCID 11430—
SolventDimethylformamideHCID 6228—
Productp-DodecyloxybenzaldehydeHCID 14106999.8%

Reaction Conditions

Temperature65 °C

Reaction Steps

4-Hydroxybenzaldehyde (673 mg, 5.5 mmol), 1-bromododecane (1.25 g, 5 mmol) and potassium carbonate (859 mg, 6.22 mmol) were added to dimethylformamide (3 ml), and they were stirred at 65° C. for 18 hours. After the completion of the reaction followed by the extraction with ethyl acetate, 4-dodecyloxybenzaldehyde (yield: 1.45 g, 99%) was obtained in the form of white crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326701B2
Source datasetuspto-grants-2008_02
ORD IDord-56cbc2e31fe2402ca7a24e3159782ab4
Source noteuspto-grants-2008_02