HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichlorobenzeneboronic acid → HCID 59654661, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichlorobenzeneboronic acid | HCID 2734330 | — |
| Reactant | (3-[(5-Bromo-furan-2-carbonyl)-amino]-phenyl)-acetic Acid Methyl Ester | HCID 59654700 | — |
| Product | HCID 59654661 | HCID 59654661 | — |
Reaction Steps
Methyl ester (16) (100 mg, 0.30 mmol) was coupled to 3,4-dichloro-phenylboronic acid (61 mg, 0.33 mmol) using Method E. The crude compound was purified by column chromatography, eluting in 17% EtOAc in heptane to give the title compound. Yield: 33 mg, 27%; LC/MS tr 1.70 min; MS(ES+) m/z 404, 406 (M+H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326732B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-52e20f7f0f334d8d99fca3bd23f83126 |
| Source note | uspto-grants-2008_02 |