5-Phenylfuran-2-carboxylic acid → 6-[(5-Phenyl-furan-2-carbonyl)-amino]-naphthalene-2-carboxylic acid methyl ester

HRID 2053173Notes

Reaction equation

HRID 2053173 reaction equation
[C:1]1([C:7]2[O:11][C:10]([C:12]([OH:14])=O)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:15][O:16][C:17]([C:19]1[CH:28]=[CH:27][C:26]2[C:21](=[CH:22][CH:23]=[C:24]([NH2:29])[CH:25]=2)[CH:20]=1)=[O:18]>>[CH3:15][O:16][C:17]([C:19]1[CH:28]=[CH:27][C:26]2[C:21](=[CH:22][CH:23]=[C:24]([NH:29][C:12]([C:10]3[O:11][C:7]([C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)=[CH:8][CH:9]=3)=[O:14])[CH:25]=2)[CH:20]=1)=[O:18]

Participants

3

Reactant 2

HCID 7362555-Phenylfuran-2-carboxylic acidHCID 11995029Methyl 6-Amino-2-naphthoate

Product 1

HCID 596546486-[(5-Phenyl-furan-2-carbonyl)-amino]-naphthalene-2-carboxylic acid methyl ester

Procedure

5-Phenyl-furan-2-carboxylic acid (56) (50 mg, 0.26 mmol) was coupled to 6-amino-naphthalene-2-carboxylic acid methyl ester (53 mg, 0.26 mmol) using Method C to give the title compound.

Sources & evidence

ORD record
ord-6b878af20ed0420abed8f1fd0160e0de
Source dataset
uspto-grants-2008_02
Patent number
US07326732B2

Reaction notes

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