HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(3-aminophenoxy)acetate → (3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenoxy)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(3-aminophenoxy)acetate | HCID 412308 | — |
| Reactant | 5-(3-Chlorophenyl)furan-2-carboxylic acid | HCID 736256 | — |
| Product | (3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenoxy)-acetic acid ethyl ester | HCID 59654640 | — |
Reaction Steps
Carboxylic acid (65) (67 mg, 0.3 mmol) was coupled to ethyl ester (64) (58 mg, 0.25 mmol) using Method C. The crude residue was purified by column chromatography eluting with a stepped gradient of 10-20% EtOAc in heptane to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326732B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-985823996b574632bbff8b33009b3daf |
| Source note | uspto-grants-2008_02 |