反应详情

Carboxylic acid (65) (58 mg, 0.26 mmol) was coupled to ethyl ester (60) (50 mg, 0.26 mmol) using Method C. The crude residue was purified by column chromatography eluting with a stepped gradient of 10-15% EtOAc in heptane to give the title compound.

1. customThe crude residue was purified by column chromatography
2. washeluting with a stepped gradient of 10-15% EtOAc in heptane