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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2053217Generated: October 26, 2026

3-Aminocinnamic acid ethyl ester → 3-{3-[(6-Bromo-pyridine-2-carbonyl)-amino]-phenyl}-acrylic acid ethyl ester

https://huagongshe.com/reaction/2053217

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Aminocinnamic acid ethyl esterHCID 97825—
Reactant6-Bromopyridine-2-carboxylic acidHCID 593919—
Product3-{3-[(6-Bromo-pyridine-2-carbonyl)-amino]-phenyl}-acrylic acid ethyl esterHCID 72348809—

Reaction Steps

6-Bromo-pyridine-2-carboxylic acid (127 mg, 0.63 mmol) was coupled to aniline (60)(120 mg, 0.63 mmol) using Method C to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326732B2
Source datasetuspto-grants-2008_02
ORD IDord-1d87fa4f79604e20b4c509c40defe302
Source noteuspto-grants-2008_02