Ethanol → Ethyl 3-(3-Aminophenyl)propionate

HRID 2053240Notes

Reaction equation

[NH2:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[CH:6][CH:7]=1.[CH3:13][CH2:14]O>>[CH2:13]([O:11][C:10](=[O:12])[CH2:9][CH2:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([NH2:1])[CH:3]=1)[CH3:14]

Participants

Reactant 2

HCID 702Ethanol

HCID 27354063-(3-Aminophenyl)propionic acid

Product 1

HCID 82314Ethyl 3-(3-Aminophenyl)propionate

Procedure

3-(3-Aminophenyl)propionic acid (250 mg, 1.52 mmol) was esterified with EtOH using Method A to give the title compound.

Sources & evidence

ORD record: ord-d353393eaeb545e286ddcb617eb88a83
Source dataset: uspto-grants-2008_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07326732B2

Reaction notes

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