HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(3-Aminophenyl)propionate → 3-(3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenyl)-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(3-Aminophenyl)propionate | HCID 82314 | — |
| Reactant | 5-(3,5-Dichlorophenyl)furan-2-carboxylic acid | HCID 4066369 | — |
| Product | 3-(3-{[5-(3-Chloro-phenyl)-furan-2-carbonyl]-amino}-phenyl)-propionic acid ethyl ester | HCID 59654779 | — |
Reaction Steps
Carboxylic acid (67)(58 mg, 0.26 mmol) was coupled to aniline (124)(50 mg, 0.26 mmol) using Method C. The residue was purified by column chromatography eluting with 10% EtOAc in heptane to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326732B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-d1ebf2d3e20747b298800e550b6868b0 |
| Source note | uspto-grants-2008_02 |