HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(3-Aminophenyl)propionate → HCID 59654753, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(3-Aminophenyl)propionate | HCID 82314 | — |
| Reactant | 5-(4-Fluorophenyl)furan-2-carboxylic acid | HCID 738991 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 59654753 | HCID 59654753 | — |
Reaction Steps
Carboxylic acid (76)(53 mg, 0.26 mmol) was coupled to aniline (124)(50 mg, 0.26 mmol) using Method C. During this reaction, hydrolysis occurred. The acid was re-dissolved in EtOAc (2 ml) and the organic layer was washed with 1M HCl (2×1 ml), dried (Na2SO4), filtered and the solvent removed in vacuo. The solid was recrystallised from a hot 10% EtOH in H2O mixture to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326732B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-e2441c5c10194961bdaf882066d4a56d |
| Source note | uspto-grants-2008_02 |