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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2053271Generated: October 25, 2026

Ethyl 2-(3-aminophenoxy)acetate → (3-{[6-(4-Fluoro-phenyl)-pyridine-2-carbonyl]-amino}-phenoxy)-acetic acid ethyl ester

https://huagongshe.com/reaction/2053271

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(3-aminophenoxy)acetateHCID 412308—
Reactant6-(4-Fluorophenyl)picolinic acidHCID 21081708—
Product(3-{[6-(4-Fluoro-phenyl)-pyridine-2-carbonyl]-amino}-phenoxy)-acetic acid ethyl esterHCID 59654786—

Reaction Steps

Carboxylic acid (152)(50 mg, 0.23 mmol) was coupled to aniline (64)(45 mg, 0.23 mmol) using Method C to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326732B2
Source datasetuspto-grants-2008_02
ORD IDord-fa6135ba13e94e1c9c2d03d9a4333e84
Source noteuspto-grants-2008_02