HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(3-Aminophenyl)propionate → 3-(3-{[6-(4-Fluoro-phenyl)-pyridine-2-carbonyl]amino}-phenyl)-propionic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(3-Aminophenyl)propionate | HCID 82314 | — |
| Reactant | 6-(4-Fluorophenyl)picolinic acid | HCID 21081708 | — |
| Product | 3-(3-{[6-(4-Fluoro-phenyl)-pyridine-2-carbonyl]amino}-phenyl)-propionic acid ethyl ester | HCID 59654758 | — |
Reaction Steps
Carboxylic acid (152)(50 mg, 0.23 mmol) was coupled to aniline (124)(45 mg, 0.23 mmol) using Method C. The residue was purified by column chromatography eluting with 30% EtOAc in heptane to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326732B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-d8763f8e459d46d88704b919b38558f7 |
| Source note | uspto-grants-2008_02 |