Ethyl 2-(3-aminophenoxy)acetate → HCID 59654854, compound

HRID 2053278Notes

Reaction equation

HRID 2053278 reaction equation
[Br:1][C:2]1[N:7]=[C:6]([C:8]([OH:10])=O)[CH:5]=[CH:4][CH:3]=1.[CH2:11]([O:13][C:14](=[O:24])[CH2:15][O:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH2:23])[CH:18]=1)[CH3:12]>>[CH2:11]([O:13][C:14](=[O:24])[CH2:15][O:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH:23][C:8]([C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([Br:1])[N:7]=2)=[O:10])[CH:18]=1)[CH3:12]

Participants

3

Reactant 2

HCID 412308Ethyl 2-(3-aminophenoxy)acetateHCID 5939196-Bromopyridine-2-carboxylic acid

Product 1

HCID 59654854HCID 59654854, compound

Procedure

6-Bromo-pyridine-2-carboxylic acid (250 mg, 1.24 mmol) was coupled to aniline (64)(241 mg, 1.24 mmol) using Method C to give the title compound.

Sources & evidence

ORD record
ord-a1e677573aca48baadcce804336b2fe3
Source dataset
uspto-grants-2008_02
Patent number
US07326732B2

Reaction notes

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