HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromopyridine-2-carboxylic acid → 6-Bromo-pyridine-2-carboxylic acid (3-cyanomethoxy-phenyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromopyridine-2-carboxylic acid | HCID 593919 | — |
| Reactant | 2-(3-Aminophenoxy)acetonitrile | HCID 18789699 | — |
| Product | 6-Bromo-pyridine-2-carboxylic acid (3-cyanomethoxy-phenyl)-amide | HCID 59654623 | — |
Reaction Steps
6-Bromo-pyridine-2-carboxylic acid (341 mg, 1.69 mmol) was coupled to aniline (172)(250 mg, 1.69 mmol) using Method C. The residue was purified by column chromatography eluting with 20% EtOAc in heptane to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326732B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-ba6ebdc928d74ce2b1f55c88180ee072 |
| Source note | uspto-grants-2008_02 |