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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2053313Generated: October 28, 2026

Diisopropylethylamine → HCID 178518195, compound

https://huagongshe.com/reaction/2053313

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactantphenylalaninol, (R)-HCID 853475—
Reactant(5Z)-2-(methylthio)-5-(6-quinolinylmethylidene)-1,3-thiazol-4(5H)-oneHCID 58585737—
ProductHCID 178518195HCID 178518195—

Reaction Steps

Similar procedure as described in example 1b was used, starting from 2-methylsulfanyl-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one, (R)-1-hydroxymethyl-2-phenyl-ethylamine and DIEA to give 2-((R)-1-hydroxymethyl-2-phenyl-ethylamino)-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one. LC-MS m/e 390 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326786B2
Source datasetuspto-grants-2008_02
ORD IDord-2371c31cb9934a68ab22c8b5302d7ea6
Source noteuspto-grants-2008_02