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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2053320Generated: October 30, 2026

Diisopropylethylamine → HCID 178518190, compound

https://huagongshe.com/reaction/2053320

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant(R)-beta-aminophenethyl alcoholHCID 2724025—
Reactant(5Z)-2-(methylthio)-5-(6-quinolinylmethylidene)-1,3-thiazol-4(5H)-oneHCID 58585737—
ProductHCID 178518190HCID 178518190—

Reaction Steps

Similar procedure as described in example 1b was used, starting from 2-methylsulfanyl-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one, (R)-(−)-phenylglycinol and DIEA to give 2-((R)-2-hydroxy-1-phenyl-ethylamino)-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one. LC-MS m/e 376 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326786B2
Source datasetuspto-grants-2008_02
ORD IDord-7ef6575a46304123bdab43563b42e188
Source noteuspto-grants-2008_02