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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2053343Generated: October 30, 2026

1-Amino-2-propanol → HCID 178468252, compound

https://huagongshe.com/reaction/2053343

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Amino-2-propanolHCID 4—
ReactantDiisopropylethylamineHCID 81531—
Reactant(5Z)-2-(methylthio)-5-(6-quinolinylmethylidene)-1,3-thiazol-4(5H)-oneHCID 58585737—
ProductHCID 178468252HCID 178468252—

Reaction Steps

Similar procedure as described in example 1b was used, starting from 2-methylsulfanyl-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one, 2-hydroxy-propylamine and DIEA to give 2-(2-hydroxy-propylamino)-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one. LC-MS m/e 314 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326786B2
Source datasetuspto-grants-2008_02
ORD IDord-9dadeafe27a64f8da567e5337996ffaf
Source noteuspto-grants-2008_02