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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2053346Generated: October 31, 2026

Diisopropylethylamine → HCID 178518192, compound

https://huagongshe.com/reaction/2053346

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant(2R)-2-amino-2-cyclohexylethan-1-olHCID 13617488—
Reactant(5Z)-2-(methylthio)-5-(6-quinolinylmethylidene)-1,3-thiazol-4(5H)-oneHCID 58585737—
ProductHCID 178518192HCID 178518192—

Reaction Steps

Similar procedure as described in example 1b was used, starting from 2-methylsulfanyl-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one, (R)-1-cyclohexyl-2-hydroxy-ethylamine and DIEA to give 2-((R)-1-cyclohexyl-2-hydroxy-ethylamino)-5-[1-quinolin-6-yl-meth-(Z)-ylidene]-thiazol-4-one. LC-MS m/e 382 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326786B2
Source datasetuspto-grants-2008_02
ORD IDord-450d71c21f734c81ac1483b6159022fa
Source noteuspto-grants-2008_02