HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → (+/-)-5-(2,6-Dichlorophenyl)-3-(3-nitrophenyl)-2-isoxazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,6-Dichlorostyrene | HCID 34254 | — |
| Reactant | alpha-Chloro-3-nitrobenzaldoxime | HCID 2756318 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (+/-)-5-(2,6-Dichlorophenyl)-3-(3-nitrophenyl)-2-isoxazoline | HCID 69221841 | — |
Reaction Steps
3-Nitro-N-hydroxybenzenecarboximidoyl chloride (1.16 g, 5.78 mmol) and 2,6-dichlorostyrene (1.0 g, 5.78 mmol) were dissolved in anhydrous THF (20 mL) and triethylamine (1.21 mL, 8.67 mmol). Upon addition of triethylamine a while solid formed. After 3 h this solid was collected by filtration under reduced pressure to provide the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326790B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-73f9f14d9f514b97b18ad1a80624141f |
| Source note | uspto-grants-2008_02 |