HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11528683, compound → (6S)-6-METHYL-7-(TETRAHYDRO-2H-PYRAN-2-YLOXY)HEPTAN-2-ONE
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11528683 | HCID 11528683 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (6S)-6-METHYL-7-(TETRAHYDRO-2H-PYRAN-2-YLOXY)HEPTAN-2-ONE | HCID 11622725 | 100% |
Reaction Steps
A 50 g solution (222.9 mmol) of (S)-6-methyl-7-[(RS)-(3,4,5,6-tetrahydro-2H-pyran-2-yl)oxy]hept-3-in-2-one and 5 g palladium on carbon (10% Pd/C) in 400 ml of THF is hydrogenated for one hour at 8 bar hydrogen at room temperature. The catalyst is then filtered off, rewashed with little solvent and the solvent is removed in vacuo. 50.9 g of product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326798B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-f341d14b8c8540eabe506c23d45a5a08 |
| Source note | uspto-grants-2008_02 |