2-Amino-5-chlorobenzophenone → HCID 136018635, compound

HRID 2053411Notes

Reaction equation

HRID 2053411 reaction equation
[CH3:1][C:2]1[O:6][N:5]=[C:4]([CH2:7][C:8]([OH:10])=O)[CH:3]=1.[NH2:11][C:12]1[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][C:13]=1[C:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=O>>[Cl:18][C:15]1[CH:14]=[C:13]2[C:12](=[CH:17][CH:16]=1)[NH:11][C:8](=[O:10])[C:7]([C:4]1[CH:3]=[C:2]([CH3:1])[O:6][N:5]=1)=[C:19]2[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

3

Reactant 2

HCID 128702-Amino-5-chlorobenzophenoneHCID 122782545-Methyl-3-isoxazoleacetic acid

Product 1

HCID 136018635HCID 136018635, compoundYield 69%

Procedure

Synthesized from (5-methyl-isoxazol-3-yl)-acetic acid (J. Med. Chem., 34(2), 518, 1991) and (2-amino-5-chloro-phenyl)-phenyl-methanone according to general procedure 2. Yield 69%.

Sources & evidence

ORD record
ord-d4238a23f1ba491399463d1dbe1b280f
Source dataset
uspto-grants-2008_02
Patent number
US07326788B2

Reaction notes

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