(2-methyl-1,3-thiazol-4-yl)acetic acid → HCID 59654967, compound

HRID 2053413Notes

Reaction equation

HRID 2053413 reaction equation
[CH3:1][C:2]1[S:3][CH:4]=[C:5]([CH2:7][C:8]([OH:10])=O)[N:6]=1.[NH2:11][C:12]1[CH:19]=[CH:18][C:15]([C:16]#[N:17])=[CH:14][C:13]=1[C:20](=O)[C:21]1[CH:26]=[CH:25][C:24]([CH2:27][CH3:28])=[CH:23][CH:22]=1>>[CH2:27]([C:24]1[CH:23]=[CH:22][C:21]([C:20]2[C:13]3[C:12](=[CH:19][CH:18]=[C:15]([C:16]#[N:17])[CH:14]=3)[NH:11][C:8](=[O:10])[C:7]=2[C:5]2[N:6]=[C:2]([CH3:1])[S:3][CH:4]=2)=[CH:26][CH:25]=1)[CH3:28]

Participants

3

Reactant 2

HCID 854632(2-methyl-1,3-thiazol-4-yl)acetic acidHCID 69216568HCID 69216568, compound

Product 1

HCID 59654967HCID 59654967, compoundYield 27%

Procedure

Synthesized from (2-methyl-thiazol-4-yl)-acetic acid and 4-Amino-3-(4-ethyl-benzoyl)-benzonitrile according to general procedure 2. Yield 27%.

Sources & evidence

ORD record
ord-a16002984d224c90808f1b673f95c257
Source dataset
uspto-grants-2008_02
Patent number
US07326788B2

Reaction notes

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