1-Pyrrolidineethanamine → HCID 135462065, compound

HRID 2053416Notes

Reaction equation

HRID 2053416 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][C:7](=[O:12])[C:6]([C:13]1[O:17][N:16]=[C:15]([CH:18]=O)[CH:14]=1)=[C:5]2[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[N:26]1([CH2:31][CH2:32][NH2:33])[CH2:30][CH2:29][CH2:28][CH2:27]1>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][C:7](=[O:12])[C:6]([C:13]1[O:17][N:16]=[C:15]([CH2:18][NH:33][CH2:32][CH2:31][N:26]3[CH2:30][CH2:29][CH2:28][CH2:27]3)[CH:14]=1)=[C:5]2[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 13441-PyrrolidineethanamineHCID 136338674HCID 136338674, compound

Product 1

HCID 135462065HCID 135462065, compoundYield 53%

Procedure

From 5-(6-chloro-2-oxo-4-phenyl-1,2-dihydro-quinolin-3-yl)-isoxazole-3-carboxaldehyde and 2-pyrrolidin-1-yl-ethylamine according to procedure 24. Yield 53%.

Sources & evidence

ORD record
ord-d33d0fe07568493e9e6befab8ac43949
Source dataset
uspto-grants-2008_02
Patent number
US07326788B2

Reaction notes

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