HCID 135489139, compound → HCID 135421239, compound

Participants

Reaction Steps

A flask charged with 3-(3-methyl-isoxazol-5-yl)-6-nitro-4-phenyl-1H-quinolin-2-one (0.2 g, 0.58 mmol)(Example 51), 50 mg of 10% Pd/C, and 10 mL of methanol was shaken on a Parr apparatus under 15 PSI of H2 for 8 hrs. The solution was filtered and concentrated to give 0.18 g (100%) of the title compound as a white solid. 1H NMR (400 MHz, CD3OD) δ 7.44 (m, 3H), 7.22 (m, 3H), 7.04 (m, 1H), 6.50 (m, 1H), 6.34 (s, 1H), 2.20 (s, 3H). Mass spectrum (ESI, m/z) calcd. for C19H15N3O2 317.1, found 318.1 (M+H).

Provenance & Evidence