Sodium Hydroxide → HCID 10324744, compound

HRID 2053485Notes

Reaction equation

HRID 2053485 reaction equation
[CH3:1][C:2]1([CH3:36])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([Se:14][C:15]#[C:16][C:17]3[CH:26]=[CH:25][C:20]([C:21]([O:23]C)=[O:22])=[CH:19][CH:18]=3)[CH:5]=[C:4]([O:27][CH2:28][C:29]3[CH:34]=[CH:33][C:32]([CH3:35])=[CH:31][CH:30]=3)[C:3]1=2.[OH-].[Na+]>>[CH3:1][C:2]1([CH3:36])[CH2:11][CH2:10][C:9]([CH3:12])([CH3:13])[C:8]2[CH:7]=[C:6]([Se:14][C:15]#[C:16][C:17]3[CH:26]=[CH:25][C:20]([C:21]([OH:23])=[O:22])=[CH:19][CH:18]=3)[CH:5]=[C:4]([O:27][CH2:28][C:29]3[CH:34]=[CH:33][C:32]([CH3:35])=[CH:31][CH:30]=3)[C:3]1=2

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 86599529HCID 86599529, compound

Product 1

HCID 10324744HCID 10324744, compound

Procedure

In a manner similar to Example 1g, by reacting 650 mg (1.2 mmol) of methyl 4-[5,5,8,8-tetramethyl-4-(4-methylbenzyloxy)-5,6,7,8-tetrahydro-2-naphthylselanylethynyl]benzoate with 240 mg of sodium hydroxide. A yellow crystallized solid is obtained (m=580 mg; yield=91%; m.p.=254° C.).

Workup

  1. customA yellow crystallized solid
  2. customis obtained (m=580 mg; yield=91%; m.p.=254° C.)

Sources & evidence

ORD record
ord-e48f53c922c84147b9ce7dff034018e8
Source dataset
uspto-grants-2008_02
Patent number
US07326803B2

Reaction notes

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