Sodium Hydroxide → HCID 86599537, compound

HRID 2053489Notes

Reaction equation

HRID 2053489 reaction equation
[CH3:1][C:2]1([CH3:39])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([Se:14][C:15]#[C:16][C:17]3[CH:26]=[CH:25][C:20]([C:21]([O:23]C)=[O:22])=[CH:19][CH:18]=3)[CH:5]=[C:4]([O:27][CH2:28][C:29]3[C:38]4[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=4)[CH:32]=[CH:31][CH:30]=3)[C:3]1=2.[OH-].[Na+]>>[CH3:1][C:2]1([CH3:39])[CH2:11][CH2:10][C:9]([CH3:12])([CH3:13])[C:8]2[CH:7]=[C:6]([Se:14][C:15]#[C:16][C:17]3[CH:26]=[CH:25][C:20]([C:21]([OH:23])=[O:22])=[CH:19][CH:18]=3)[CH:5]=[C:4]([O:27][CH2:28][C:29]3[C:38]4[C:33](=[CH:34][CH:35]=[CH:36][CH:37]=4)[CH:32]=[CH:31][CH:30]=3)[C:3]1=2

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 86599536HCID 86599536, compound

Product 1

HCID 86599537HCID 86599537, compound

Procedure

In a manner similar to that of Example 1g, by reacting 400 mg (0.7 mmol) of methyl 4-[5,5,8,8-tetramethyl-4-(naphthylmethoxy)-5,6,7,8-tetrahydro-2-naphthylselanylethynyl]benzoate with 140 mg of sodium hydroxide. A white crystallized solid is obtained (m=258 mg; yield=65%; m.p.=254° C.).

Workup

  1. customA white crystallized solid
  2. customis obtained (m=258 mg; yield=65%; m.p.=254° C.)

Sources & evidence

ORD record
ord-f6f6a6992e474a559df4dfe510f05b01
Source dataset
uspto-grants-2008_02
Patent number
US07326803B2

Reaction notes

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