1-Butanol → Butyl oxoacetate

HRID 2053500Notes

Reaction equation

HRID 2053500 reaction equation
[CH2:1]([OH:5])[CH2:2][CH2:3][CH3:4].[CH:6]([CH:8]=[O:9])=[O:7]>C(O)CCCCCCC>[C:8]([O:5][CH2:1][CH2:2][CH2:3][CH2:4][CH2:1][CH2:2][CH2:3][CH3:4])(=[O:9])[CH:6]=[O:7].[C:8]([O:5][CH2:1][CH2:2][CH2:3][CH3:4])(=[O:9])[CH:6]=[O:7]

Participants

5

Reactant 2

HCID 2631-ButanolHCID 7860Glyoxal2×

Product 2

HCID 80521Butyl oxoacetateHCID 19834511Octyl oxoacetate

Reagents, catalysts & solvents 1

HCID 9571-OctanolSolvent

Procedure

5.17 g of the butanol solution of glyoxal obtained in Example 2-11, 9.62 g of 1-octanol, and 0.6 g of the above-mentioned metal-loading carrier were put into an autoclave, and an oxidation reaction was conducted by the same operation as in Example 2-11. The reaction solution thus obtained was analyzed, which revealed the glyoxal conversion to be 90%, and the combined 1-octyl glyoxylate and 1-butyl glyoxylate (the product) selectivity and yield to be 74% and 67%, respectively.

Workup

  1. customan oxidation reaction
  2. customThe reaction solution thus obtained

Sources & evidence

ORD record
ord-3b39c16de8b145658d7beb85bca752c7
Source dataset
uspto-grants-2008_02
Patent number
US07326806B2

Reaction notes

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