1-(4-(6-(4-Methoxybenzylamino)pyrimidin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)urea → 1-(4-(2-Carbamoylpyridin-4-yloxy)-3,5-difluorophenyl)-3-(2-(4-fluorophenyl)acetyl)urea
Reaction equation
[CH3:20][O:21][c:22]1[cH:23][cH:24][c:25]([CH2:26][NH:27][c:28]2[n:29][cH:30][n:31][c:32]([O:33][c:34]3[cH:35][cH:36][c:37]([NH:38][C:42](=[O:43])[NH:44][C:45]([CH2:46][c:47]4[cH:48][cH:49][c:50]([F:53])[cH:51][cH:52]4)=[O:54])[cH:39][c:40]3[F:41])[cH:55]2)[cH:56][cH:57]1.[NH2:1][c:2]1[cH:3][c:4]([F:19])[c:5]([O:6][c:7]2[cH:8][c:9]([C:13](=[O:14])[NH2:15])[n:10][cH:11][cH:12]2)[c:16]([F:18])[cH:17]1>>[NH:1]([c:2]1[cH:3][c:4]([F:19])[c:5]([O:6][c:7]2[cH:8][c:9]([C:13](=[O:14])[NH2:15])[n:10][cH:11][cH:12]2)[c:16]([F:18])[cH:17]1)[C:42](=[O:43])[NH:44][C:45]([CH2:46][c:47]1[cH:48][cH:49][c:50]([F:53])[cH:51][cH:52]1)=[O:54]Participants
3
Sources & evidence
- ORD record
- ord-44fb123b3c3043f59e116c222b83fa10
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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