HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → N-(4-bromophenyl)-N-methylbenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | Benzenamine, 4-bromo-N-methyl- | HCID 2757052 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-(4-bromophenyl)-N-methylbenzenesulfonamide | HCID 5171346 | — |
Reaction Steps
A solution of 0.61 g (3.3 mmol) of 4-bromo-N-methylaniline and 0.5 mL (3.92 mmol) of benzenesulfonyl chloride in 5 mL of pyridine was stirred for 12 h at rt. After that time the pyridine was removed by azeotropic distillation with heptane. The residue was purified by chromatography on silica (hexanes:EtOAc, 9:1) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326812B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-1038a538cf484ed19eb4763bb3b5b3d4 |
| Source note | uspto-grants-2008_02 |