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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2053697Generated: October 30, 2026

Phenylboronic Acid → 3,5-Difluorobiphenyl

https://huagongshe.com/reaction/2053697

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylboronic AcidHCID 66827—
Reactant1-Bromo-3,5-difluorobenzeneHCID 136313—
Product3,5-DifluorobiphenylHCID 1302239191.1%

Reaction Steps

Combine 1-bromo-3,5-difluorobenzene (0.863 mL, 7.50 mmol) and phenylboronic acid (1.22 g, 10.00 mmol) and subject to conditions described in Method G to yield 1.3 g of 3,5-difluorobiphenyl.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07326731B2
Source datasetuspto-grants-2008_02
ORD IDord-d35d1ea48cbc4bfb87a842aed1ca3003
Source noteuspto-grants-2008_02