HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → HCID 178481038, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | 1-Methylpiperazin-2-one | HCID 4399042 | — |
| Reactant | HCID 69309742 | HCID 69309742 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178481038 | HCID 178481038 | 8.7% |
Reaction Steps
Prepared analogously to Example 19c from 2-chloro-4-[N-(5-chlorobenzimidazol-2-ylmethyl)carbamoyl]benzoic acid, TBTU, diisopropylethylamine, and N-methylpiperazinone in N,N-dimethylformamide. Yield: 8.7%; C21H19Cl2N5O3 (460.32); mass spectrum: (M+H)+=460/462/464 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-f6189123d5be4e4d9dbec629f560fadf |
| Source note | uspto-grants-2008_02 |