HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → HCID 178464826, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | Dichloromethane methanol | HCID 21226129 | — |
| Reactant | HCID 178464822 | HCID 178464822 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178464826 | HCID 178464826 | 46% |
Reaction Steps
Prepared analogously to Example 85 from rac.-3-chloro-N-[1-(5-chloro-1H-benzimidazol-2-yl)ethyl]4-(thiazolidin-3-ylcarbonyl)benzamide and 3-chloroperoxybenzoic acid in dichloromethane/glacial acetic acid. Yield: 46%; Rf value: 0.20 (silica gel; dichloromethane/methanol=9:1); C20H18Cl2N4O3S (465.36); mass spectrum: (M+H)+=465/467 (chlorine isotope) and (M−H)−=463/465 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-6a917420e20c452288d1faad36608c41 |
| Source note | uspto-grants-2008_02 |