HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → HCID 178481038, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | 1-Methylpiperazin-2-one | HCID 4399042 | — |
| Reactant | HCID 178523088 | HCID 178523088 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178481038 | HCID 178481038 | 9% |
Reaction Steps
Prepared analogously to Example 1g from 3-chloro-N-(5-chloro-1H-benzimidazol-2-ylmethyl)-4-carboxybenzamide, TBTU, diisopropylethylamine, and 1-methylpiperazin-2-one in DMF. Yield: 9%; C21H19C12N5O3 (460.32); mass spectrum: (M+H)+=460/462/464 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-d6ebe200e7944cb8b0223eacb468981f |
| Source note | uspto-grants-2008_02 |