HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → HCID 178427195, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | Dichloromethane ethanol | HCID 21584144 | — |
| Reactant | HCID 178503696 | HCID 178503696 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178427195 | HCID 178427195 | 57% |
Reaction Steps
Prepared analogously to Example 85 from N-[(1S)-1-(5-chloro-1H-benzimidazol-2-yl)-3-methylsulfanylpropyl]-3-methyl-4-(pyrrolidin-1-ylcarbonyl)benzamide and 3-chloroperoxybenzoic acid in dichloromethane/glacial acetic acid. Yield: 57%; Rf value: 0.15 (silica gel; dichloromethane/ethanol=9:1); C24H27ClN4O3S (487.02); mass spectrum: (M+H)+=487/489 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-3e0a886a7b4d40f3b4e8de698a0aed22 |
| Source note | uspto-grants-2008_02 |