HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 3-Chloro-4-(pyrrolidin-1-ylsulfonyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | 3-Chloro-4-(pyrrolidin-1-ylsulfonyl)benzonitrile | HCID 69312500 | — |
| Product | 3-Chloro-4-(pyrrolidin-1-ylsulfonyl)benzoic acid | HCID 69311154 | 89% |
Reaction Steps
Prepared analogously to Example 1f from 3-chloro-4-(pyrrolidin-1-ylsulfonyl)benzonitrile and sodium hydroxide solution in ethanol. Yield: 89% of theory; C11H21ClNO4S (289.74); mass spectrum: (M+H)+=290/292 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-bdb21e8938ca48128aaa1d11f8d3d6e9 |
| Source note | uspto-grants-2008_02 |