Ethanol → HCID 69312605, compound

HRID 2053945Notes

Reaction equation

HRID 2053945 reaction equation
[N:1]1([C:10]2[CH:17]=[CH:16]C(C#N)=[CH:12][C:11]=2[C:18]([F:21])([F:20])[F:19])[C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:4]=2[N:3]=[CH:2]1.[OH-:22].[Na+].[CH2:24]([OH:26])[CH3:25]>>[N:1]1([C:10]2[CH:17]=[CH:16][C:25]([C:24]([OH:22])=[O:26])=[CH:12][C:11]=2[C:18]([F:21])([F:20])[F:19])[C:5]2[CH2:6][CH2:7][CH2:8][CH2:9][C:4]=2[N:3]=[CH:2]1

Participants

4

Reactant 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 69311412HCID 69311412, compound

Product 1

HCID 69312605HCID 69312605, compoundYield 94%

Procedure

Prepared analogously to Example 1f from 4-(4,5,6,7-tetrahydrobenzimidazol-1-yl)-3-trifluoromethylbenzonitrile and sodium hydroxide solution in ethanol. Yield: 94%; C15H13F3N2O2 (310.28); mass spectrum: (M+H)+=311 and (M−H)−=309

Sources & evidence

ORD record
ord-c1cece00cd93473cb93cf5906669f10d
Source dataset
uspto-grants-2008_02
Patent number
US07326791B2

Reaction notes

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