HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178462098, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | HCID 178462099 | HCID 178462099 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 178462098 | HCID 178462098 | 55% |
Reaction Steps
Prepared analogously to Example 17 from 4-[3-(tert-butoxycarbonylamino)methyl-5,6-dihydro-4H-cyclopentapyrazol-1-yl]-N-[(1S)-1-(5-chloro-1H-benzimidazol-2-yl)ethyl]-3-trifluoromethylbenzamide and trifluoroacetic acid. Yield: 55%; Rf value: 0.25 (silica gel; dichloromethane/methanol=9:1); C24H22ClF3N6O (502.93); mass spectrum: (M−H)−=503/505 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-ed9d6a9a161b4bffb2059ad56733c6d2 |
| Source note | uspto-grants-2008_02 |