HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → HCID 178464801, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1-(2-Piperidinylmethyl)piperidine | HCID 254290 | — |
| Reactant | HCID 178464831 | HCID 178464831 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 178464801 | HCID 178464801 | — |
Reaction Steps
Prepared analogously to Example 1d from rac.-2-chloro-4-{N-[1-(5-chloro-1H-benzimidazol-2-yl)ethyl]aminocarbonyl}benzoic acid, rac.-2-(piperidin-1-ylmethyl)piperidine, PFTU, and diisopropylethylamine in DMSO at ambient temperature. HPLC-MS results: retention time: 4.09 minutes; C28H33Cl2N5O2 (542.51); mass spectrum: (M−H)−=542/544/546 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-d8faae650a11447a9fdff7e1b97c192f |
| Source note | uspto-grants-2008_02 |