HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → HCID 178464802, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | N-cyclohexyl-N-methyl-N-(piperidin-2-ylmethyl)amine | HCID 13578532 | — |
| Reactant | HCID 178464831 | HCID 178464831 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 178464802 | HCID 178464802 | — |
Reaction Steps
Prepared analogously to Example 1d from rac.-2-chloro-4-{N-[1-(5-chloro-1H-benzimidazol-2-yl)ethyl]aminocarbonyl}benzoic acid, 2-(N-cyclohexyl-N-methylaminomethyl)piperidine, PFTU, and diisopropylethylamine in DMSO at ambient temperature. HPLC-MS results: retention time: 4.25 minutes; C30H37Cl2N5O2 (570.56); mass spectrum: (M−H)−=570/572/574 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-e92ec3cf59df4316ad5a2e724a6251f0 |
| Source note | uspto-grants-2008_02 |