HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorine → HCID 178464411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | N-Ethylethylenediamine | HCID 66071 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 178464831 | HCID 178464831 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 178464411 | HCID 178464411 | — |
Reaction Steps
Prepared analogously to Example 1d from rac.-2-chloro-4-{N-[1-(5-chloro-1H-benzimidazol-2-yl)ethyl]aminocarbonyl}benzoic acid, N-(2-aminoethyl)ethylamine, PFTU, and diisopropylethylamine in DMSO at ambient temperature. HPLC-MS results: retention time: 3.82 minutes; C21H23Cl2N5O2 (448.35); mass spectrum: (M−H)−=447/449/451 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-c17b7d3c5f684e81bebe407359049a77 |
| Source note | uspto-grants-2008_02 |