HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpiperidine → HCID 178464798, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpiperidine | HCID 7974 | — |
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 178464831 | HCID 178464831 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 178464798 | HCID 178464798 | — |
Reaction Steps
Prepared analogously to Example 1d from rac.-2-chloro-4-{N-[1-(5-chloro-1H-benzimidazol-2-yl)ethyl]aminocarbonyl}benzoic acid, rac.-2-methylpiperidine, PFTU, and diisopropylethylamine in DMSO at ambient temperature. HPLC-MS results: retention time: 4.58 minutes; C23H24Cl2N4O2 (459.38); mass spectrum: (M−H)−=458/460/462 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-626076fbd7fc4beaa47145c4820b3fc7 |
| Source note | uspto-grants-2008_02 |