HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178462079, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | BROMINE CHLORIDE (BrCl) | HCID 61697 | — |
| Reactant | Ammonia methanol dichloromethane | HCID 21584172 | — |
| Reactant | HCID 178462080 | HCID 178462080 | — |
| Product | HCID 178462079 | HCID 178462079 | 58% |
Reaction Steps
Prepared analogously to Example 17 from 3-bromo-4-[(2R/S)-2-(tert-butoxycarbonyl-aminomethyl)thiazolidin-3-ylcarbonyl]-N-[(1S)-1-(5-chloro-1H-benzimidazol-2-yl)ethyl]benzamide and trifluoroacetic acid. Yield: 58%; Rf value: 0.30 (silica gel: dichloromethane/methanol/ammonia=9:1:0.1); C21H21BrClN5O2S (522.853); mass spectrum: (M+H)+=522/524/526 (bromo-chlorine. isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-628596e168e7487db6b19b03cd08400d |
| Source note | uspto-grants-2008_02 |