HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178427126, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Chlorine | HCID 24526 | — |
| Reactant | HCID 178427127 | HCID 178427127 | — |
| Solvent | Dichloromethane ethanol | HCID 21584144 | — |
| Product | HCID 178427126 | HCID 178427126 | 99% |
Reaction Steps
Prepared analogously to Example 17 from N-[(1R,2S)-2-tert-butoxy-1-(5-chloro-1H-benzimidazol-2-yl)propyl]-4-(2,5-dihydropyrrol-1-ylcarbonyl)-3-methylbenzamide, and trifluoroacetic acid. Yield: 99%; Rf value: 0.48 (silica gel: dichloromethane/ethanol=9:1); C23H23ClN4O3 (438.913); mass spectrum: (M+H)+=439/441 (chlorine isotope) and (M−H)-=437/439 (chlorine isotope).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-b1492f59f4a6483abbf3632e17f43a0d |
| Source note | uspto-grants-2008_02 |