HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 178427153, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3-Methyl 4-(pyrrolidin-1-ylcarbonyl)benzoic acid | HCID 12068686 | — |
| Reactant | HCID 22609213 | HCID 22609213 | — |
| Reactant | HCID 178461865 | HCID 178461865 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178427153 | HCID 178427153 | 12% |
Reaction Steps
Prepared analogously to Example 1g from 3-methyl 4-(pyrrolidin-1-ylcarbonyl)benzoic acid, TB TU, diisopropylethyl amine, and (1S)-1-(5-hydroxy-1H-benzimidazol-2-yl)ethylamine in tetrahydrofuran. Yield: 12%; Rf value: 0.40 (silica gel: dichloromethane/ethanol/ammonia=9:1:0.1); C22H24N4O3 (392.457); mass spectrum: (M+H)+=393
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-63990ad1339447a9b6c7d225f50cf3de |
| Source note | uspto-grants-2008_02 |