HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 178427166, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | N-Methyl-L-proline | HCID 643474 | — |
| Reactant | HCID 178427160 | HCID 178427160 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 178427166 | HCID 178427166 | — |
Reaction Steps
Prepared analogously to Example 1d from N-[(1S)-5-amino-1-(5-chloro-1H-benzimidazol-2-yl)pentyl]-3-methyl-4-(pyrrolidin-1-ylcarbonyl)benzamide, PFTU, diisopropylethylamine, and (S)-1-methylpyrrolidine-2-carboxylic acid in dimethylsulfoxide. HPLC-MS results: retention time: 2.03 minutes; C31H39ClN6O3 (579.15); mass spectrum: (M−H)−=578.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07326791B2 |
| Source dataset | uspto-grants-2008_02 |
| ORD ID | ord-9dc9bcd7cc1348b083ece241c648003d |
| Source note | uspto-grants-2008_02 |